Effects of Ashwagandha in Aging Males
TL;DR: This study investigated the effects of Ashwagandha (Withania somnifera) on aging, overweight males, revealing no significant difference in fatigue, vigor, or sexual well-being compared to a placebo, but showed an increase in DHEA-S and testosterone levels, suggesting potential benefits for hormonal health.
Key Highlights:
Background and Purpose:
Fatigue is common among adults, impacting self-care and quality of life, and may indicate aging or future health issues. This study aimed to explore Ashwagandha’s impact on fatigue, vigor, and hormone levels in aging men.
Methodology:
A 16-week, randomized, double-blind, placebo-controlled crossover study with 57 participants aged 40–70, examining the effects of Ashwagandha on mood and hormone levels.
Findings:
No significant difference in fatigue, vigor, or sexual and psychological well-being was found between the Ashwagandha and placebo groups.
Ashwagandha intake led to an 18% increase in DHEA-S and 14.7% increase in testosterone, without significant changes in cortisol and estradiol levels.
Conclusions:
While Ashwagandha did not significantly impact fatigue or vigor compared to a placebo, it was associated with beneficial hormonal changes. Further research with larger samples is needed to confirm these findings.
Implications for Future Research:
The study suggests potential hormonal benefits of Ashwagandha for aging males, emphasizing the need for larger, more detailed studies to explore its effects and mechanisms further.
